EQUIOXX® (firocoxib)
A caring choice for equine joint pain.
EQUIOXX is a non-steroidal anti-inflammatory drug (NSAID), that is:
- Proven to relieve the pain and inflammation of equine OA.1
- Prove in both field and laboratory trials to be safe at the recommended dose.2
- Easily administered, once-a-day oral paste that is well-accepted by 98% of horses.3
- 24 hours of targeted pain relief.4
EQUIOXX is the only NSAID approved for use up to 14 consecutive days by the American Quarter Horse Association5 (AQHA) and the United States Equestrian Federation (SEF), when used at it's recommended dose at least 12 hours prior to competing.6 This gives you the freedom to treat during longer events without skipping days.
EQUIOXX is the first coxib class Non-Steroidal Anti-Inflammatory Drug (NSAID) approved for horses in the US, formulated especially to alleviate the pain and inflammation associated with equine osteoarthritis.
As a coxib class NSAID, EQUIOXX targets COX-2 (cyclooxygenase-2), which helps generate chemicals that are responsible for pain and inflammation, while sparing COX-1 (cycloxygenase-1), which helps maintain normal bodily functions such as renal blood flow and gastric mucosal protection.*
* Clinical relevance has not been determined.
1 Data on file at Merial, "Clinical Experience Report, PHN 471, Target Animal Safety Evaluation, Firocoxib (ML-1,785,713) Oral Paste for Horses."
2 Data on file at Merial, Safety Study, PR&D 0016801.
3 Data on file at Merial. Multicenter Field Study, PR&D 0084201-07/09-10.
4 EQUIOXX product label.
5 American Quarter Horse Association. Show rules and regulations. Official Handbook of Rules and Regulations. 2008:128. Available at: http://www.aqha.com/association/registration/pdf/showrules_08.pdf. Accessed February 1, 2008.
6 United States Equestrian Federation. Drugs and Medications Guidelines. 2007:2-3. Available at: http://www.usef.org/documents/competitions/2007/2007DrugsMedsGuidelines.pdf. Accessed February 13, 2008.
As with any prescription medication, prior to use, a veterinarian should perform a physical examination and review the horse's medical history. A veterinarian should advise horse owners to observe for signs of potential drug toxicity. As a class, nonsteriodal anti-inflammatory drugs may be associated with gastrointestinal and renal toxicity. Use with other NSAIDs, corticosteroids or nephrotoxic medication should be avoided. EQUIOXX has not been tested in horses less than 1 year of age or in breeding horses, or pregnant or lactating mares. For additional information please refer to the prescribing information or visit www.equioxx.com.
